More than a million people in the UK have type 2 diabetes and the number is rising sharply. Genes play an important role in the development of diabetes, although the mechanisms for this are not well understood. The Norfolk Diabetes Case Control Study will help to identify genetic factors linked to type 2 diabetes and its complications. The study aims to contribute to a better understanding of how diabetes develops and how it can be prevented and treated better.

This was a case-control study of type 2 diabetes which recruited 6974 prevalent cases of Type 2 diabetes from practices in Norfolk, with cases then matched to EPIC controls. This provided a population-based case-control study which contributes to our understanding of the genetics of type 2 diabetes.

Status

Completed.

Unit role

Unit responsible for data and samples and continuing analysis.

Funding

This work was funded by the Medical Research Council (MRC) and the Wellcome Trust in collaboration with the Norfolk and Norwich University Hospitals NHS Foundation Trust in Norfolk. Continued preservation and use is funded by Unit core MRC grant.

Publications

Norfolk Diabetes Case-Control Study publications on the MRC Epidemiology Unit publications database.

Data sharing

We welcome proposals for projects and aim to make data as widely available as possible whilst safeguarding the privacy of our participants, protecting confidential data and maintaining the reputations of our studies and participants. Please see our Data Sharing pages for more information.