Information about genetic and phenotypic risk of type 2 diabetes (T2DM) is now widely available but whether such information generates anxiety and/or motivates behaviour change is unknown. In the Diabetes Risk Communication trial 569 middle-aged, non-diabetic adults who consented to taking part received either standard lifestyle advice alone (control group), or in combination with either genetic or a phenotypic risk estimate for T2DM. The primary outcome of objectively measured physical activity (combined sensing) and secondary outcomes (self-reported diet weight, worry, anxiety, and perceived risk) were measured at 8 weeks post-intervention. A post-intervention questionnaire assessed acceptance and putative mediating variables.
Status
Data collection complete, analysis and publication on-going.
Unit Role
Unit led with responsibility for data.
Funding
MRC core funded.
Data sharing
We welcome proposals for projects and aim to make data as widely available as possible whilst safeguarding the privacy of our participants, protecting confidential data and maintaining the reputations of our studies and participants. Please see our Data Sharing pages for more information.
Publications
DRCT publications on the MRC Epidemiology Unit publications database.
Selected publications
- Brage S, Westgate K, Wijndaele K, Godinho J, Griffin S, Wareham N. Evaluation of a method for minimising diurnal information bias in objective sensor data. ICAMPAM (Amherst) Conference Proceeding 2013.
- Wijndaele K, Bourdeaudhuij I, Godino J, Lynch BM, Griffin SJ, Kate Westgate K, Brage S. Reliability & Validity of a Domain-Specific Last-7-Day Sedentary Time Questionnaire. Med Sci Sports Exerc (2014)