PhD Student

Aetiology and Mechanisms of Diabetes and Related Metabolic Disorders of Later Life and Wellcome Trust 4-year Programme in Metabolic and Cardiovascular Diseases

Has now left the Unit

Current work and interests

Chen was a PhD student on the Wellcome Trust 4-year Programme in Metabolic and Cardiovascular Diseases, working under the supervision of Dr Claudia Langenberg to characterize gene-specific effects of LDL cholesterol on type 2 diabetes using metabolomics.

Background and experience

Chen’s Masters study was in molecular and cell biology in the University of Alberta in Canada, after which she moved to Cambridge, UK for PhD training in genetic epidemiology. Her current project studies the role of genomic markers of ageing, including telomere length, DNA methylation and chromosome loss, in determining the risk of metabolic disease.

Publications

• MRC Epidemiology Unit publications on the Publications Database

Selected publications

• Klemm RW, Norton JP, Cole RA, Li CS et al. A conserved role for atlastin GTPases in regulating lipid droplet size.. Cell reports (2013) 3(5):1465-75.
• Chen L et al. Roles of acyl-CoA: diacylglycerol acyltransferases 1 and 2 in triacylglycerol synthesis and secretion in primary hepatocytes. Arteriosclerosis, thrombosis, and vascular biology (2015) 35(5):1080-91.

Links

Cambridge Metabolic Network