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Estimating the global burden of disease attributable to excess sodium within the GBD2010 study

Abstract
Sodium intake increases blood pressure, a risk factor for cardiovascular disease. In Global Burden of Disease (GBD) study we carried out a study to model the estimated effect of sodium consumption on mortality. We quantified global sodium intake, by age, sex, and country, based on urinary and dietary surveys from 66 countries representing 74.1% of the world population. We quantified blood pressure effects of sodium, by age, race, and hypertension, in a new meta-analysis of 107 trials; and blood pressure effects on cardiovascular mortality, by age, from meta-analysis of cohorts. Cause-specific mortality was derived from the 2010 Global Burden of Diseases Study. We estimated cardiovascular impacts of current sodium intake, compared with reference intake of 2.0 g/d, using comparative risk assessment, by age, sex, and country. In this modelling study, 1.65 million cardiovascular deaths were attributed to sodium consumption above a reference level of 2.0 g/d.

About Dr John Powles
Dr Powles graduated in Medicine from Sydney University, Australia in 1968. He subsequently spent 4 years in the UK then 16 years at Monash Medical School in Melbourne before coming to Cambridge in 1991. In Cambridge he has worked especially on East/West health differences in Europe, public health policies in developed countries and graduate education in public health. (For the University’s 800th anniversary he also helped create the walking tour 800 years of death and disease in Cambridge). Since retiring in 2011 he has continued teaching and research as an Honorary Senior Visiting Fellow. Department of Public Health and Primary Care profile.

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