MRC Epidemiology Unit
New research has found four genes with some of the largest known effects on the timing of menopause discovered to date, providing new insight into links between menopause timing and […]
Blood proteins predict the risk of developing more than 60 diseases
Research on thousands of proteins measured from a drop of blood demonstrates the ability of proteins to predict the onset of many diverse diseases for the first time. The researchers […]
Largest ever genetic study of age of puberty in girls shows links with weight gain
Genes can indirectly influence the age at which girls have their first period by accelerating weight gain in childhood, a known risk factor for early puberty, according to new research […]
Rare gene variants conferring up to 6-fold increase in obesity risk hint at new mechanism affecting appetite control
A study led by Medical Research Council (MRC) researchers has identified genetic variants in two genes that have some of the largest impacts on obesity risk discovered to date. The […]
Identifying novel sex- and age-specific gene variants that influence obesity risk
From influencing how our body stores fat to how our brain regulates appetite, hundreds of genes, along with environmental factors, collectively determine our weight and body size. Now, researchers add […]
Can improving cardiorespiratory fitness help prevent type 2 diabetes? Genetics may hold the answer
Higher cardiorespiratory fitness is associated with higher insulin sensitivity and lower risk of type 2 diabetes, but until now it hasn’t been clear if the relationship is causal, and the […]
Research challenges current thinking on the genetic causes of very early menopause
The genetic causes of very early menopause will have to be reconsidered after researchers found that nearly all women who carried variations thought to cause the condition in fact had […]
Genetic variants influencing human fertility identified in study of nearly 800,000 individuals.
Fertility is influenced by mechanisms that influence both reproductive biology and human behaviour, according to the largest study to date identifying genetic determinants of the number of children an individual […]
Fitness levels can be predicted using wearable devices…and no treadmill required!
Cambridge researchers have developed a method for measuring overall fitness accurately on wearable devices – and more robustly than current consumer smartwatches and fitness monitors – without the wearer needing […]
Wearable device study in 88,000 people shows the heart health benefits of more intense physical activity
Increasing physical activity of any intensity is beneficial for health, but new research published today in the European Heart Journal shows that there is a greater reduction in cardiovascular disease […]
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