MRC Epidemiology Unit
Open Science is an increasingly important movement across many disciplines. It involves initiatives and resources that make scientific research – including data, publications and software – freely accessible not just […]
Identification of disease-causing proteins leads to new potential treatments for diseases like diabetes
New research has identified hundreds of proteins that might contribute to the onset of common, chronic metabolic diseases such as type 2 diabetes, and consequently pathways to potential treatments. The […]
Revealing the chemical fingerprints of healthy metabolism and disease
An international collaboration led by scientists from the University of Cambridge and Berlin Institute of Health at Charité (BIH) has discovered more than 300 regions in the genome that contribute […]
Metabolomic study links inhaled cortical steroid treatment for asthma to adrenal suppression
Inhaled cortical steroids (ICS) can help patients manage asthma symptoms, and recent updates to asthma treatment guidelines have expanded recommendations for low-dose treatment. But concerns persist that ICS may reduce […]
New study finds shared origins for individual chronic diseases in multimorbidity
A new study published today in Nature Medicine has identified key risk factors that increase the likelihood of individuals developing not only one but multiple non-communicable diseases, which include cardiovascular disease, […]
Discovery of genetic regulators of human metabolism and health
An international team led by researchers at the MRC Epidemiology Unit has used a cross-platform approach across several large human studies to identify hundreds of novel genetic variants that regulate […]
Moderate exercise in middle and older age cuts time spent in hospital
Men and women aged 40-79 are at significantly lower (25-27%) risk of long or frequent hospital admissions if they do some form of physical activity, a new paper from the […]
Testosterone levels affect risk of metabolic disease and cancers
Having genetically higher testosterone levels increases the risk of metabolic diseases such as type 2 diabetes in women, while reducing the risk in men. Higher testosterone levels also increase the […]
Keeping active or becoming more active in middle and older age linked to longer life
Meeting minimum public health recommendations could prevent nearly one in two deaths linked to physical inactivity Keeping physically active or becoming more active during middle and older age is associated […]
Gene variations that reduce ability to store fat around the hips linked to higher risk of diabetes and heart attacks
People who are less likely to put on excess fat around their hips due to their genes are at higher risk of type 2 diabetes and heart attacks, according to […]